USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

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Searching in 'USC-OGP 2-DE database' for entry matching: O60610 USC-OGP 2-DE database:  O60610 O60610 General information about the entry View entry in simple text format Entry name DIAP1_HUMAN Primary accession number O60610 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Protein diaphanous homolog 1; AltName: Full=Diaphanous-related formin-1; Short=DRF1;. Gene name Name=DIAPH1 Synonyms=DIAP1 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_4-5 {PLATELET 4-5} Homo sapiens (Human)   map experimental info   PLATELET_4-5 MAP LOCATIONS: SPOT OGP-0039: pI=4.83; Mw=62063 SPOT OGP-0044: pI=4.84; Mw=56645 Cross-references UniProtKB/Swiss-Prot O60610; DIAP1_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name DIAP1_HUMAN Primary accession number O60610 Secondary accession number(s) A6NF18 B7ZKW2 E9PEZ2 Q17RN4 Q59FH8 Q9UC76 Sequence was last modified on  November 25, 2008 (version 2) Annotations were last modified on  March 15, 2017 (version 169) Name and origin of the protein Description RecName: Full=Protein diaphanous homolog 1; AltName: Full=Diaphanous-related formin-1; Short=DRF1; Gene name Name=DIAPH1 Synonyms=DIAP1 Encoded on Name=DIAPH1; Synonyms=DIAP1 Keywords Acetylation; Actin-binding; Alternative splicing; Cell membrane; Cell projection; Coiled coil; Complete proteome; Cytoplasm; Cytoskeleton; Deafness; Direct protein sequencing; Epilepsy; Hearing; Membrane; Non-syndromic deafness; Phosphoprotein; Reference proteome; Repeat. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL AF051782; AAC05373.1; -; mRNA EMBL AB209482; BAD92719.1; ALT_INIT; mRNA EMBL AC008781; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL BC117257; AAI17258.1; -; mRNA EMBL BC143413; AAI43414.1; -; mRNA EMBL AK023345; BAB14533.1; ALT_SEQ; mRNA CCDS CCDS43373.1; -. [O60610-3]; . CCDS CCDS43374.1; -. [O60610-1]; . RefSeq NP_001073280.1; NM_001079812.2. [O60610-3]; . RefSeq NP_005210.3; NM_005219.4. [O60610-1]; . UniGene Hs.529451; -; . ProteinModelPortal O60610; -; . SMR O60610; -; . BioGrid 108073; 51; . IntAct O60610; 29; . MINT MINT-1198324; -; . STRING 9606.ENSP00000381565; -; . iPTMnet O60610; -; . PhosphoSitePlus O60610; -; . SwissPalm O60610; -; . BioMuta DIAPH1; -; . OGP O60610; -; . EPD O60610; -; . MaxQB O60610; -; . PaxDb O60610; -; . PeptideAtlas O60610; -; . PRIDE O60610; -; . DNASU 1729; -; . Ensembl ENST00000389054; ENSP00000373706; ENSG00000131504. [O60610-1]; . Ensembl ENST00000518047; ENSP00000428268; ENSG00000131504. [O60610-3]; . GeneID 1729; -; . KEGG hsa:1729; -; . UCSC uc063iba.1; human. [O60610-1]; . CTD 1729; -; . DisGeNET 1729; -; . GeneCards DIAPH1; -; . GeneReviews DIAPH1; -; . HGNC HGNC:2876; DIAPH1; . HPA HPA004916; -; . HPA HPA076913; -; . MalaCards DIAPH1; -; . MIM 124900; phenotype; . MIM 602121; gene; . MIM 616632; phenotype; . neXtProt NX_O60610; -; . OpenTargets ENSG00000131504; -; . Orphanet 90635; Autosomal dominant non-syndromic sensorineural deafness type DFNA; . PharmGKB PA27333; -; . eggNOG KOG1924; Eukaryota; . eggNOG ENOG410Y29H; LUCA; . GeneTree ENSGT00760000118986; -; . HOGENOM HOG000293231; -; . HOVERGEN HBG051357; -; . InParanoid O60610; -; . KO K05740; -; . OMA MTSFVKD; -; . PhylomeDB O60610; -; . TreeFam TF315383; -; . Reactome R-HSA-5663220; RHO GTPases Activate Formins; . Reactome R-HSA-6785631; ERBB2 Regulates Cell Motility; . Reactome R-HSA-6798695; Neutrophil degranulation; . ChiTaRS DIAPH1; human; . GeneWiki DIAPH1; -; . GenomeRNAi 1729; -; . PRO PR:O60610; -; . Proteomes UP000005640; Chromosome 5; . Bgee ENSG00000131504; -; . CleanEx HS_DIAPH1; -; . ExpressionAtlas O60610; baseline and differential; . Genevisible O60610; HS; . GO GO:0005829; C:cytosol; TAS:Reactome; . GO GO:0101003; C:ficolin-1-rich granule membrane; TAS:Reactome; . GO GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell; . GO GO:0072686; C:mitotic spindle; IDA:BHF-UCL; . GO GO:0005886; C:plasma membrane; TAS:Reactome; . GO GO:0032587; C:ruffle membrane; IEA:UniProtKB-SubCell; . GO GO:0030667; C:secretory granule membrane; TAS:Reactome; . GO GO:0044325; F:ion channel binding; IPI:BHF-UCL; . GO GO:0005102; F:receptor binding; NAS:ProtInc; . GO GO:0003723; F:RNA binding; IDA:UniProtKB; . GO GO:0030041; P:actin filament polymerization; IEA:InterPro; . GO GO:0071420; P:cellular response to histamine; IMP:BHF-UCL; . GO GO:0007010; P:cytoskeleton organization; IMP:UniProtKB; . GO GO:0043312; P:neutrophil degranulation; TAS:Reactome; . GO GO:0030335; P:positive regulation of cell migration; IEA:Ensembl; . GO GO:0035372; P:protein localization to microtubule; IMP:BHF-UCL; . GO GO:2000145; P:regulation of cell motility; TAS:Reactome; . GO GO:0008360; P:regulation of cell shape; IMP:UniProtKB; . GO GO:0032886; P:regulation of microtubule-based process; IMP:UniProtKB; . GO GO:0051279; P:regulation of release of sequestered calcium ion into cytosol; IMP:BHF-UCL; . GO GO:0007605; P:sensory perception of sound; TAS:ProtInc; . InterPro IPR016024; ARM-type_fold; . InterPro IPR014767; DAD_dom; . InterPro IPR010465; Drf_DAD; . InterPro IPR015425; FH2_Formin; . InterPro IPR010472; FH3_dom; . InterPro IPR027653; Formin_Diaph1; . InterPro IPR009408; Formin_homology_1; . InterPro IPR014768; GBD/FH3_dom; . InterPro IPR010473; GTPase-bd; . PANTHER PTHR23213:SF278; PTHR23213:SF278; 1; . Pfam PF06345; Drf_DAD; 1; . Pfam PF06346; Drf_FH1; 1; . Pfam PF06367; Drf_FH3; 1; . Pfam PF06371; Drf_GBD; 1; . Pfam PF02181; FH2; 1; . SMART SM01139; Drf_FH3; 1; . SMART SM01140; Drf_GBD; 1; . SMART SM00498; FH2; 1; . SUPFAM SSF48371; SSF48371; 1; . PROSITE PS51231; DAD; 1; . PROSITE PS51444; FH2; 1; . PROSITE PS51232; GBD_FH3; 1; .

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